NEW YORK — New York Yankees manager Aaron Boone was ejected for the fourth time this season and second time in a four-game span when he argued with Edwin Moscoso over the umpire’s strike zone during Thursday night’s game against the Baltimore Orioles.

Boone held up four fingers while arguing with Moscoso, signaling he thought the umpire missed four calls. Boone also may have gotten spit on Moscoso while arguing, then after the ejection argued with first base umpire Chris Guccione.

The 50-year-old was ejected moments after Gunnar Henderson lined out to first to end the top of the third. Henderson worked a six-pitch walk in the first in which Moscoso called balls on three borderline pitches. Henderson laid off two pitches on the outside corner called balls in his third-inning at-bat.

Boone was ejected against Cleveland on April 12, against Toronto on May 15 and against Cincinnati on Sunday. He has been ejected 50 times in five-plus seasons as Yankees manager.