Farley was not home at the time of the explosion but was at the property speaking with police early Tuesday morning.
Aerial footage of the lakeside home from QCNews.com showed the residence was reduced to rubble. Iredell County said the residence was 6,300 square feet and would be ruled a complete loss, along with multiple vehicles parked on site.
Fire and emergency rescue officials confirmed one male was deceased and another was transported to a local hospital with non-life-threatening injuries.
Farley, 24, played at Virginia Tech and was a first-round pick of the Titans in 2021. He had multiple back surgeries in college and landed on injured reserve in 2022 to undergo another procedure, a microdiscectomy, after playing in nine games.